Endocrine Abstracts

In the cardiovascular system, aldosterone promotes inflammation, tissue remodeling and endothelial dysfunction. In diet-induced obesity, lipid accumulation involves acceleration of preadipocyte differentiation into mature adipocytes. Mutually exerted control mechanisms may exist between aldosterone secretion and fat: circulating aldosterone is increased in proportion to fat mass in humans and fat tissue expresses mineralocorticoid receptors (MR). Here we tested whether or not ...